Publikationen

Dietmar Krex, Barbara Klink, Christian Hartmann, Andreas von Deimling, Torsten Pietsch, Matthias Simon, Michael Sabel, Joachim P. Steinbach, Oliver Heese, Guido Reifenberger, Michael Weller, Gabriele Schackert fort he German Glioma Network (2007)
Long-term survival with glioblastoma multiforme.
Brain. 2007 Oct;130(Pt 10):2596-606. Epub 2007 Sep 4.


Michael Weller, Jörg Felsberg, Christian Hartmann, Hilmar Berger, Joachim P. Steinbach, Johannes Schramm, Manfred Westphal, Gabriele Schackert, Matthias Simon, Jörg C. Tonn, Oliver Heese, Dietmar Krex, Guido Nikkhah, Torsten Pietsch, Otmar Wiestler, Guido Reifenberger, Andreas von Deimling, Markus Loeffler (2009)
Molecular Predictors of Progression-Free and Overall Survival in Patients With Newly Diagnosed Glioblastoma: A Prospective Translational Study of the German Glioma Network.
J Clin Oncol. 2009 Dec 1;27(34):5743-50. Epub 2009 Oct 5.


Temme A, Geiger KD, Wiedemuth R, Conseur K, Pietsch T, Felsberg J, Reifenberger G, Tatsuka M, Hagel C, Westphal M, Berger H, Simon M, Weller M, Schackert G. (2010)
Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation.
J Neuropathol Exp Neurol. 2010 Jun;69(6):632-42.


Christian Hartmann, Bettina Hentschel, Wolfgang Wick, David Capper, Jörg Felsberg, Matthias Simon, Manfred Westphal, Gabriele Schackert, Richard Meyermann, Torsten Pietsch, Guido Reifenberger, Michael Weller, Markus Loeffler, Andreas von Deimling (2010).
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas
Acta Neuropathol. 2010 Dec;120(6):707-18. Epub 2010 Nov 19.


O. Heese, M. Schmidt, S. Nickel, H. Berger, R. Goldbrunner, J.C. Tonn, O. Bähr, J.P. Steinbach, M. Simon, J. Schramm, D. Krex, G. Schackert, T. Reithmeier, G. Nikkhah, M. Löffler, M. Weller, M. Westphal, For the German Glioma Network (2010)
Complementary therapy use in patients with glioma: An observational study.
Neurology. 2010 Dec 14;75(24):2229-35.


Christian Hartmann, Bettina Hentschel, Marcos Tatagiba, Johannes Schramm, Oliver Schnell, Clemens Seidel, Robert Stein, Guido Reifenberger, Torsten Pietsch, Andreas von Deimling, Markus Loeffler, and Michael Weller; for the German Glioma Network (2011)
Molecular markers in low-grade gliomas: predictive or prognostic?
Clin Cancer Res. 2011 Jul 1;17(13):4588-99. Epub 2011 May 10.


Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, Westphal M, Schackert G, Wilhelm Kreth F, Pietsch T, Loeffler M, Weller M, Reifenberger G, Tonn JC; for the German Glioma Network(2011)
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6, and PMS2 in paired primary and recurrent glioblastomas.
Int J Cancer. 2011 Aug 1;129(3):659-70.


David Capper, Matthias Simon, Claus-Dieter Langhans, Jürgen G. Okun, Jörg C. Tonn, Michael Weller, Andreas von Deimling, Christian Hartmann, For the German Glioma Network (2011)
2-hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size.
Int J Cancer. 2012 Aug 1;131(3):766-8. Epub 2011 Nov 2.


Reifenberger G, Hentschel B, Felsberg J, Schackert G, Simon M, Schnell O, Westphal M, Wick W, Pietsch T, Löffler M, Weller M; for the German Glioma Network (2011)
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
Int J Cancer. 2012 Sep 15;131(6):1342-50. Epub 2012 Jan 11.


C. Seidel, B. Hentschel, M. Simon, O. Schnell, O. Heese, M. Tatagiba, D. Krex, T. Reithmeier, A. Kowoll, M. Weller, W. Wick (2013)
A comprehensive analysis of vascular complications in 3,889 glioma patients from the German Glioma Network.
J Neurol. 2013 Mar;260(3):847-55. Epub 2012 Oct 27.


Hartmann C, Hentschel B, Simon M, Westphal M, Schackert G, Tonn JC, Loeffler M, Reifenberger G, Pietsch T, von Deimling A, Weller M; for the German Glioma Network (2013)
Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations.
Clin Cancer Res. 2013 Sep 15;19(18):5146-57. Epub 2013 Aug 5.


Heese O, Vogeler E, Martens T, Schnell O, Tonn JC, Simon M, Schramm J, Krex D, Schackert G, Reithmeier T, Nikkhah G, Sabel M, Steiger HJ, Schlegel U, Löffler M, Weller M, Westphal M; for the German Glioma Network (2013)
End-of-life caregivers' perception of medical and psychological support during the final weeks of glioma patients: a questionnaire-based survey.
Neuro Oncol. 2013 Sep;15(9):1251-6. Epub 2013 Jun 28.


Wolfgang Wick, Christoph Meisner, Bettina Hentschel, Michael Platten, Alissa Schilling, Benedikt Wiestler, Michael Sabel, Susanne Koeppen, Ralf Ketter, Markus Weiler, Ghazaleh Tabatabai, Andreas von Deimling, Dorothee Gramatzki, Manfred Westphal, Gabriele Schackert, Markus Loeffler, Matthias Simon, Guido Reifenberger, Michael Weller (2013)
Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation.
Neurology. 2013 Oct 22;81(17):1515-22. Epub 2013 Sep 25.


Kreth FW, Thon N, Simon M, Westphal M, Schackert G, Nikkhah G, Hentschel B, Reifenberger G, Pietsch T, Weller M, Tonn JC; for the German Glioma Network (2013)
Gross total but not incomplete resection of glioblastoma prolongs survival in the era of radiochemotherapy.
Ann Oncol. 2013 Dec;24(12):3117-23. [Epub 2013 Oct 14].


Blaes J, Weiler M, Sahm F, Hentschel B, Osswald M, Czabanka M, Thomé CM, Schliesser MG, Pusch S, Luger S, Winkler F, Radbruch A, Jugold M, Simon M, Steinbach JP, Schackert G, Tatagiba M, Westphal M, Tonn JC, Gramatzki D, Pietsch T, Hartmann C, Glimm H, Vajkoczy P, von Deimling A, Platten M, Weller M, Wick W. (2014).
NDRG1 prognosticates the natural course of disease in WHO grade II glioma.
J Neurooncol. 2014 Mar;117(1):25-32. Epub 2014 Jan 7.


Weller M, Kaulich K, Hentschel B, Felsberg J, Gramatzki D, Pietsch T, Simon M, Westphal M, Schackert G, Tonn JC, von Deimling A, Davis T, Weiss WA, Loeffler M, Reifenberger G; the German Glioma Network. (2013)
Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy.
Int J Cancer. 2014 May 15;134(10):2437-47.


Riehmer V, Gietzelt J, Beyer U, Hentschel B, Westphal M, Schackert G, Sabel MC, Radlwimmer B, Pietsch T, Reifenberger G, Weller M, Weber RG, Loeffler M; for the German Glioma Network (2014)
Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma.
Genes Chromosomes Cancer. 2014 Jul;53(7):589-605. Epub 2014 Apr 4.


Reifenberger G, Weber RG, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel MC, Gramatzki D, Felsberg J, Hartmann C, Steinbach JP, Schlegel U, Wick W, Radlwimmer B, Pietsch T, Tonn JC, von Deimling A, Binder H, Weller M, Loeffler M; for the German Glioma Network. (2014)
Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.
Int J Cancer. 2014 Oct 15;135(8):1822-31. Epub 2014 Mar 28.


Weller M, Weber RG, Willscher E, Riehmer V, Hentschel B, Kreuz M, Felsberg J, Beyer U, Löffler-Wirth H, Kaulich K, Steinbach JP, Hartmann C, Gramatzki D, Schramm J, Westphal M, Schackert G, Simon M, Martens T, Boström J, Hagel C, Sabel M, Krex D, Tonn JC, Wick W, Noell S, Schlegel U, Radlwimmer B, Pietsch T, Loeffler M, von Deimling A, Binder H, Reifenberger G (2015)
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups.
Acta Neuropathol. 2015 May;129(5):679-93. [Epub 2015 Mar 18].


Gramatzki D, Roth P, Felsberg J, Hofer S, Rushing EJ, Hentschel B, Westphal M, Krex D, Simon M, Schnell O, Wick W, Reifenberger G, Weller M.
Chemotherapy for intracranial ependymoma in adults.
BMC Cancer. 2016 Apr 23;16:287.


Pitter KL, Tamagno I, Alikhanyan K, Hosni-Ahmed A, Pattwell SS, Donnola S, Dai C, Ozawa T, Chang M, Chan TA, Beal K, Bishop AJ, Barker CA, Jones TS, Hentschel B, Gorlia T, Schlegel U, Stupp R, Weller M, Holland EC, Hambardzumyan D.
Corticosteroids compromise survival in glioblastoma.
Brain. 2016 May;139(Pt 5):1458-71. Epub 2016 Mar 28.


Gramatzki D, Kickingereder P, Hentschel B, Felsberg J, Herrlinger U, Schackert G, Tonn JC, Westphal M, Sabel M, Schlegel U, Wick W, Pietsch T, Reifenberger G, Loeffler M, Bendszus M, Weller M (2017)
Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.
Neurology. 2017 Apr 11;88(15):1422-1430. Epub 2017 Mar 15.


Cimino PJ, Zager M, McFerrin L, Wirsching HG, Bolouri H, Hentschel B, von Deimling A, Jones D, Reifenberger G, Weller M, Holland EC.
Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.
Acta Neuropathol Commun. 2017 May 22;5(1):39.


Jörg Felsberg, Bettina Hentschel, Kerstin Kaulich, Dorothee Gramatzki, Angela Zacher, Bastian Malzkorn, Marcel Kamp, Michael Sabel, Matthias Simon, Manfred Westphal, Gabriele Schackert, Jörg C. Tonn, Torsten Pietsch, Andreas von Deimling, Markus Loeffler, Guido Reifenberger, and Michael Weller, for the German Glioma Network (2017)
Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors.
Clin Cancer Res. 2017 Nov 15;23(22):6846-6855. Epub 2017 Aug 29.


Beyer U, Brand F, Martens H, Weder J, Christians A, Elyan N, Hentschel B, Westphal M, Schackert G, Pietsch T, Hong B, Krauss JK, Samii A, Raab P, Das A, Dumitru CA, Sandalcioglu IE, Hakenberg OW, Erbersdobler A, Lehmann U, Reifenberger G, Weller M, Reijns MAM, Preller M, Wiese B, Hartmann C, Weber RG.
Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.

Acta Neuropathol. 2017 Dec;134(6):905-922. Epub 2017 Oct 13.


Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM.
Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.
Cancer Cell. 2018 Jul 9;34(1):163-177.e7.


Hendrik Witt, Dorothee Gramatzki, Bettina Hentschel, Kristian W. Pajtler, Jörg Felsberg, Gabriele Schackert, Markus Löffler, David Capper, Felix Sahm, Martin Sill, Andreas von Deimling, Marcel Kool, Ulrich Herrlinger, Manfred Westphal, Torsten Pietsch, Guido Reifenberger, Stefan M. Pfister, Jörg C. Tonn, and Michael Weller; fort he German Glioma Network (2018)
DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment.
Neuro Oncol. 2018 Jul 24. [Epub ahead of print]


Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM
DNA methylation-based classification of central nervous system tumours.
Nature. 2018 Mar 22;555(7697):469-474. Epub 2018 Mar 14.